John Powers may refer to:
Academia and writing
John Powers (academic) (born 1957), American-born Australian professor of Asian studies and Buddhism
John Powers (film critic) (born 1951), American film critic, columnist, and writer
John Powers (sports journalist) (born 1948), American journalist and author
John Emory Powers (1837–1919), copywriter
John J. Powers (food scientist) (1918–2014), professor emeritus of food science
John R. Powers (1945–2013), American novelist and playwright
Government, law, and politics
John Powers (Canadian politician) (1894–1977), Ottawa alderman and controller in the mid 20th century
John Powers (Illinois politician) (1852–1930), Chicago alderman in the late 19th and early 20th centuries
John Powers (mayor), former mayor of Spokane, Washington
John A. Powers (1922–1979), public affairs officer for NASA
John C. Powers (1883–1914), Arizona deputy sheriff better known as Maricopa Slim
John E. Powers (1910–1998), American politician in the Massachusetts Senate
Baseball
John Powers (baseball) (1929–2001), baseball outfielder
Cricket
John Powers (cricketer) (1868–1939), right-handed batsman from Leicestershire
Football
John Powers (American football coach), college football player and coach
John Powers (tight end) (1940–1978), American National Football League football player
Others
John Powers (musician), saxophonist, former member of American ska band Spring Heeled Jack
John Holbrook Powers (1831–1918), Nebraska pioneer
John James Powers (1912–1942), United States Navy officer and Medal of Honor recipient
John Robert Powers (1892–1977), American actor and owner of a modeling agency