Luke may refer to:
People
Luke (given name), including a list of people and fictional characters with the name
Luke (surname), including a list of people with the name
Christianity
Gospel of Luke, a Christian Gospel
Luke the Evangelist, author of the Gospel of Luke
Music
Luke (album), by Steve Lukather
Luke (French band)
Luke Records, a record label
Dr. Luke, American songwriter and record producer Łukasz Sebastian Gottwald (born 1973)
Uncle Luke, also known as Luke, American rapper Luther Roderick Campbell (born 1960)
"LUKE", a song by Susumu Hirasawa from Glory Wars
Places
Luke (Čajniče), a village in the municipality of Čajniče, Bosnia and Herzegovina
Luke (Hadžići), a village in Sarajevo Canton, Bosnia and Herzegovina
Luke (Pale), a village in the municipality of Pale, Bosnia and Herzegovina
Luke, Vareš, a village in the municipality of Vareš, Bosnia and Herzegovina
Luke, Estonia, a village in Nõo Parish, Tartu County, Estonia
Luke Manor
Luke, North Macedonia, a village in Kriva Palanka
Luke (Ivanjica), a village in the municipality of Ivanjica, Serbia
Luke, Maryland, a town in the United States
Luke, an oldentime English overname of the Dutch placename Luik, now known as Liege, Belgium; also, an English word for goods such as velvet and iron from Luik
Luke Air Force Base, Glendale, Arizona, United States
Luke Field, Ford Island, Hawaii, United States, name of the Army Air Force airfield from 1919 to c. 1939
Luke railway station, Luke, Manitoba, Canada
Other uses
Luke, Natural Resources Institute Finland (Luonnonvarakeskus)
Luke, a 1970s British boutique run by Gordon Luke Clarke
Baron Luke, a title in the Peerage of the United Kingdom
"Luke" (Street Level Hero), an episode of Street Level Hero