Andrew or Andy Hamilton may refer to:
Arts and entertainment
Andy Hamilton (jazz saxophonist) (1918–2012), Jamaican-born British jazz saxophonist
Andy Hamilton (pop saxophonist) (born 1953), British pop saxophonist
Andy Hamilton (born 1954), British comedian
Law and politics
Andrew Hamilton, Lord Redhouse (c.1565–1634), Scottish jurist
Andrew Hamilton (New Jersey governor) (died 1703), American colonial governor
Andrew Hamilton (lawyer) (1676–1741), Scottish attorney in colonial Pennsylvania
Andrew Jackson Hamilton (1815–1875), US congressman and provisional governor of Texas
Andrew H. Hamilton (1834–1895), US congressman
Sports
Andrew Hamilton (footballer, born 1873) (1873–1929), Scottish footballer
Andrew Hamilton (footballer, born 1882) (1882–1915), Scottish footballer
Andrew Hamilton (rugby union) (1893–1975), Scotland rugby union player
Andy Hamilton (American football) (born 1950), American football player
Sir Andrew Hamilton, 10th Baronet (born 1953), English cricketer
Andy Hamilton (darts player) (born 1967), British darts player
Andrew Hamilton (rugby league) (born 1971), Australian rugby league player
Andrew Hamilton (canoeist), British canoeist
Others
Andrew Hamilton of Goslington (died 1592), Scottish landowner
Andrew Hamilton (priest) (died 1754), Anglican priest in Ireland
Andrew D. Hamilton (born 1952), British chemist
Andy Hamilton (author) (born 1974), British author
Other uses
SS Andrew Hamilton, American Liberty ship