David or Dave Clarke may refer to:
Entertainment
David Clarke (actor) (1908–2004), American actor
Dave Clarke (musician) (born 1948), American singer, guitarist, and keyboard player
Dave Clarke (DJ) (born 1968), English techno DJ
David Clarke, a character in the TV series Revenge
Politics
David Clarke (Australian politician) (born 1947), member of New South Wales Legislative Council
David Clarke (sheriff) (born 1956), former sheriff of Milwaukee County
David A. Clarke (1943–1997), founding member of the Washington, D.C. city council
Football
Dave Clarke (English footballer) (born 1949), English football goalkeeper
Dave Clarke (Scottish footballer) (born 1950), Scottish football player and manager
Dave Clarke (Canadian football) (born 1950), Canadian football player
David Clarke Sr. (born 1952), Australian rules footballer
David Clarke (footballer, born 1964), English footballer
David Clarke (Paralympic footballer) (born 1970), English five-a-side footballer
David Clarke (Australian footballer, born 1980), Australian rules footballer
David Clarke (Gaelic footballer) (born 1983), Gaelic footballer
Other sports
David Clarke (English cricketer) (born 1967), English cricketer
David Clarke (Australian cricketer) (born 1970), Australian cricketer
Dave Clarke (hurler) (born 1971), Irish hurler
David Clarke (ice hockey) (born 1981), English ice hockey player
Dave Clarke (runner) (born 1958), British distance runner
Academia
David Clarke (journalist) (born 1967), English lecturer and writer on UFO sightings since 2008
David Clarke (professor), deputy vice-chancellor of Bristol University
David L. Clarke (1937–1976), English archaeologist
David R. Clarke, material scientist and physics professor
David J. Clarke (born 1954), professor of modern and contemporary art at the University of Hong Kong
Religion
David Clarke (minister) (born 1946), moderator of the Presbyterian Church in Ireland 2006
David Clarke (priest) (1923–?), Anglican priest
Business
David S. Clarke (1942–2011), Australian chief executive and winemaker